For those people who are trying to get pregnant by the In-vitro Fertilization System (IVF), constantly testing for pregnancy is a pretty intuitive thing to do.
Especially, after the 6-day transfer of the blastocyst, many people start testing for pregnancy with their over-the-counter FRER pregnancy testing kits.
Now, sometimes they get a big fat negative (BFN) and get depressed.
Thus, to look for assurance on whether they should be further hopeful or not, people search through the internet on the topic “7dp5dt – BFN on FRER“.
Luckily for you, we have broken down everything that you need to know on 7dp5dt – BFN on FRER.
So, All you have to do is sit tight and read this discussion till the very end.
7dp5dt BFN On FRER
In simple terms, we would like to tell you that there is still a chance even if you get a BFN 7dp5dt. So, you can still get a big fat positive (BFP) even after getting a BFN 7dp5dt.
However, in order to fully understand the inner workings of the pregnancy and everything about a positive pregnancy in an In-vitro Fertilization System (IVF), you need to understand how the 5dt(5 days transfer) process is done. After knowing the steps of the 5 days blastocyst transfer process, he’ll fully understand why it is too early to lose hope at 7dp5dt.
5dt: What Does It Mean?
In the In-vitro Fertilization(IVF) System of getting pregnant, a blastocyst is cultured in a laboratory environment from an embryo.
Because the embryo is kept in the laboratory environment for 5 days, the process of transferring the blastocyst into the uterus of the woman is known as “5 days transfer”.
Now, when people use the term “7dp5dt” in any pregnancy-related forums, they usually mean the full form “7 days post 5-day transfer”. Meaning, 7 days have passed since that transference of blastocyst into the uterus of the woman.
FRER: What Does It Mean?
FRER stands for the full form “first response early result“. It is a system of testing pregnancy that can provide early results. For example, if a woman wants to know if she’s pregnant 5 to 6 days earlier before missing her period, she will have to test her pregnancy with a FRER pregnancy kit.
The best aspect of FRER pregnancy kits is that they can provide almost 95% accurate results in detecting the test line darker then control line pregnancy test at a very early stage.
On top of that, this type of pregnancy testing kit is the most efficient as you can take a pregnancy test while on your period.
Furthermore, a FRER pregnancy testing kit is most accurate because it detects the surge of hCG(Human Chorionic Gonadotropin)hormone. This particular hormone is a special type of hormone that is only released in the woman’s body when a blastocyst is fully implanted into her uterus.
This means, whenever a high amount of hCG is detected in the urine, it is almost made sure that the woman is about to become pregnant. Now, in order to indicate a positive or negative pregnancy, this is exactly what a FRER testing kit does (it indicates the presence of hCG).
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In-depth Description Of 5 Days Transfer Process:
In an In-vitro Fertilization(IVF) system, the sperm and egg are fertilized in a laboratory environment. Then, the fertile embryo is kept in the laboratory for 5 days to grow and turn into a blastocyst. After that, the blastocyst is surgically transferred into the uterus of the woman.
At this point, you need to note here that, for a natural birth, an embryo takes about 14 days to completely indicate its formation. That’s why, even in the In-vitro Fertilization(IVF) system, you’ll need 14 days to ensure a positive or negative pregnancy with 100% certainty.
Now, since the embryo is already kept in the laboratory environment for 5 days, you need to wait 9 more days to ensure the success of the pregnancy.
Well, to know exactly why you need to wait 9 more days to fully ensure a positive pregnancy, let’s get to know the events that occur days post 5 days transfer (dp5dt):
First Day (1dp5dt):
This is the first day after the 5-day transfer has occurred. In this time frame, the blastocyst begins to hatch out and its number of cells begins to multiply by dividing.
Second Day(2dp5dt):
On the second day, The blastocyst completely gets attached to the uterine line of the mother.
Third-Day (3dp5dt):
At this point, the blastocyst further attaches to the uterine line and deepens its stay. Also, on the third day, it starts the implantation process right away.
Fourth Day (4dp5dt):
On the fourth day, the blastocyst will attach to the mother’s blood supply.
Fifth Day (5dp5dt):
At the end of the 5th day of blastocyst implantation, the embryo cells divide multiple times (they multiply and generate extra cells that will later turn into the placenta and fetus).
Sixth Day (6dp5dt):
After 5 days have gone by the 6 days blastocyst or 6Dp5dt will secrete a special hormone (hCG) from the placenta. This particular hormone is detected by FRER detection kits by examining the urine sample of the mother.
Note: According to National library of medicine:
When looking at vitrified blastocysts only, there were no significant differences between day 5 and day 6 blastocysts
Seventh Day (7dp5dt):
At this point, the embryo will further secrete more hCG hormone.
8th Day ((8dp5dt):
Similar to the seventh day, the blastocyst will continue to secrete the hCG hormone even on the eighth day.
9th Day (9dp5dt):
On the 9th day, the generation of hCG hormone reaches a peak level. And, at this point, it is ensured that all types of pregnancy testers will be able to detect if the pregnancy is leading to a positive development or not.
Frequently Asked Questions:
How accurate are the FRER tests?
The First Response Early Results(FRER) testing systems are up to 99% accurate. But, the accuracy is dependent on which time frames the pregnancy testing was conducted. For example, the time period for receiving the most accurate pregnancy testing result is the 9th day past the 5-day transfer process.
How much hCG hormone is enough for the FRER distinct system to indicate a BFP?
Well, to put in numeric values, a general FRER kit will be able to detect the presence of hCG hormone even in as little levels as 6.3mlU/ml. However, the sensitivity of the FRER testing kits can vary from brand to brand.
3. Is BFP Ever Detected On 5dp5dt?
Yes, although this type of case is exceptional, it is possible to see a woman getting a BFP on 5dp5dt.
Conclusion:
So, the bottom line is that if you get a 7dp5dt – BFN on FRER, you shouldn’t be discouraged or depressed. Remember, there are 2 more days to look forward to. So, be lively and cheerful. Also, always wish for the best.
Now, even if you get a BFN on the 9th day, we would recommend you to stay optimistic. It’s because we believe that fortune only favors the brave. Therefore, keep trying until you get a BFP someday. We bid you the best of luck.
Sources:
Kaye, L., Will, E. A., Bartolucci, A., Nulsen, J., Benadiva, C., & Engmann, L. (2017, July). Pregnancy rates for single embryo transfer (SET) of day 5 and Day 6 blastocysts after cryopreservation by vitrification and slow freeze. Journal of assisted reproduction and genetics. Retrieved October 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476550/#:~:text=Ongoing%20pregnancy%20rates%20from%20day,6%20(p%20%3D%200.68).
